The 20th century witnessed the rise of noncommunicable disorders (NCDs) and the consolidation of cardiovascular disease (CVD) as the number one cause of morbidity and mortality globally. Despite great advances in understanding how CVD occurs and can be treated and prevented, still, in 2018, CVD remains on the top of disease and mortality burdens worldwide. The emergence of CVD and NCDs in general has resulted from improvements in living conditions, hygiene, sanitation, and healthcare, among others, that have contributed to substantial decreases in child and maternal mortality and to people living ever longer.